耀世平台

The Hippo Signaling Pathway - Function, Regulation, and Evolution

From STTM to 'Two-Hit' Asymmetrical amiRNAs: Harnessing RNA-based Technologies for Advanced Gene Silencing in Plants

Mismatch repair deficiency in cancer and cancer therapy

From the Nuclear Envelope to Human Disease What a Long, Strange Trip It’s Been

Functions of two humoral memory populations and their generation mechanisms

The role of lipids in mechanotransduction

Neuro-immune interactions in the gut

The Plasticity of Eukaryotic Genomes

VEGF-B: the Yin and Yang in angiogenesis

肿瘤转录组学研究与应用

Epigenetic pathways astargets in human disease

Non-image-forming photoreceptor improves image perception

Image-forming vision restoration and decoding

高等生物中转录早期调控的分子机制研究

类固醇激素膜受体亚家族的发现和GPCR的微环境药理学

植物中的RNA调控

HOW WILDLIFE FIT INTO AN URBANIZED PLANET

哺乳动物生命孕育

Molecular mechanism linking the evolution of cortical folding

INTERPRETING GENETIC VARIANTS AND DESIGNING PROTEINS USING DEEP LEARNING

Tracking specific microglial states in development and disease

Unlocking neurodegeneration through CRISPR-based functional genomics screening

The essentials of sepsis study - Cultivative or lost 40 years

DNA damage response drives childhood ALL relapse clonal evolution

WHAT CAN CHARMM-GUI DO FOR YOU?

如何在 Nature Communications 上发表高质量科研文章

Neofunctionalization of Toll signaling: the evolution of dorsoventral axis formation in insects

RNA修饰网络的形成和动态调控

The roles and features of microglia in the brain: the expected and unexpected

植物代谢的多层次调控

The Hallmarks of Cancer

Sexually Dimorphic Control of Affective State Processing and Empathic Behaviors

Frontiers of Cancer Neuroscience

植物-微生物共生的机制和应用

超级疫苗--理论假说与研究实践

胚胎发育与体细胞重编程的表观调控机制研究

Biomolecular condensates in RNA damage response

New chemical biology tools for GPCRs

Adaptive Decompositions of Radom Signals

活细胞RNA动态分析技术

Behind the scenes: publishing with Molecular Cell

The world in a drop of water: environmental DNA unveils comprehensive biodiversity and complex ecological interactions

Decoding the Epigenome in Physiology and Diseases

Allele-specific methylation analysis using long-read sequencing

Translational Chemical Biology

阿尔茨海默病发病机制和药物研发进展

Artificial intelligence to explore multimodality molecular data and accelerate biomedical knowledge discovery

Ultra-sensitive and scalable mass spectrometry-based single cell proteomics

Biochemical functions of plant NLR immune receptors -from resistosomes to second messengers

The Hippo Pathway: Signaling and Cancer

Examining populations of face-selective cells with calcium imaging in marmoset monkeys

Study the evolution of neural circuits in insects and birds

体外重塑骨髓微环境逆转造血干细胞衰老

帕金森病的干细胞治疗——从基础研究到临床转化

Cryo-EM driven paradigm shift of ABC transporter mechanism

Safe but not too safe – Human Challenge in Tuberculosis

"Manga-Managing" Blood Lipids by COPII Condensation

氨基酸感应与肿瘤微环境

Investigating and translating for potential clinical application of molecular mechanisms of genomic integrity

结直肠癌发生和转移的代谢调控

父系吸烟/尼古丁暴露对小鼠及子代的影响

把”冷门“焐热，让“热门“升华 ——我平凡科研案例背后的科学与人文思考

计算育种-从“试验选优”向“计算选优”的探索

Publishing at Cell Press

The science behind the scientific writing

Modularity-driven diversification of pathogen effectors

Phagocytosis-driven neurodegeneration and optogenetic tools for studying cell biology of the neuron

Intergration of stress by transcriptional factors and its role in aging

植物根在非生物胁迫下维持生长的分子机制

见微知著之肝癌精准诊疗

新发再发传染病病原体结构与功能研究

A new mode of parental genomic imprinting shapes the genetic control of embryos in plant ancestors

Light, energy sensing and nitrogen fixation in soybean

Unveiling the Microscopic Marvels: Navigating Biomedical Insights from 2D to 3D via Electron Microscopy

表观遗传调控机理与作物遗传育种

2023年度学术周

ABC模型花发育调控基因的结构保守性和转录后调控机制研究

Infections, immunity and B cell lymphomagenesis

Reinforcement signals broadcast by neuromodulatory systems during associative learning

Interoceptive Glucose Sensing in Flies and Mice

How genes become machines in mitochondria

Secondary siRNA pathways as key regulators of male reproductive development in plants

Epigenetic regulation in embryonic development, schizophrenia, and aging

NMDAR dysfunction in autism spectrum disorders

Multidisciplinary approach toward understanding the pathophysiology of autism

Four decades of eukaryotic DNA replication – from yeast genetics to human cryoEM structures

Dynamic Pluripotent Stem Cell States and Their Applications

The “endless forms”: Genetics, development, and evolution of flower

How supramolecular complexes are assembled for immune defense

Illuminating the Biochemical Activity Architecture of the Cell

Cryo-EM structures of natively decorated ciliary doublet microtubule and associated complexes

Coordinated regulation of Na+ extrusion and long-distance transport in plant

Metabolic Signals in Longevity Regulation across the Scale

Proximity labeling-driven understanding of plant nuclear membrane function

Light and Life：光感受与生命过程调控

调控植物碳-氨代谢平衡实现可持续“绿色革命”

Hippo signaling in organ size control and beyond

NMDA receptor diversity: from atomic structure to brain function

植物根可塑性生长发育的机理研究

Deciphering the roles of somatic mutation in human development, aging, and diseases

B细胞抗体基因高频突变的DNA柔性基础

A unified theory for Alzheimer’s disease and beyond

基因组时代的大豆分子设计育种探索

植物免疫与病原菌毒性的共进化和广谱抗病重构

From Sensitivity to Specificity: Assembly of the NAIP/NLRC4 Inflammasome

Phase separation in synapse formation and function

Enzymatic DNA Oxidation in the Control of Development and Adaptation

丁友玲：从研究生涯走上创业之路

Interactions between plants and root microbiome in rice and Arabidopsis

哺乳动物第二极体在细胞命运决定和胚胎发育中的作用

从载人深潜到MEER计划

Mechanisms and Inhibition of membrane-bound O-acyltransferases (MBOATs)

南海海洋哺乳动物观测及其生态学和演化生物学研究

RNA-programmable Cell Editing: from discovering biology to harnessing next generation genetic medicine

组织透明化技术与应用

野生动物演化与保护：基因组学与大数据视角

In situ structure and activities of methane-oxidising enzymes by cryo-electron tomography and subtomogram averaging

Phase Separation in gene expression repression

肤浅的认知，略懂皮毛

Decoding transcription regulation when life begins

Neural circuits of oxytocin release for mouse maternal behavior

The role of RNA in DNA damage repair and mitosis

2022年度学术周

Fine live imaging with light for neuroscience research

炎症小体和细胞焦亡研究历程与思考

囊膜病毒入侵机制与治疗药物研发

The driving force of alveolar development, regeneration, and fibrosis

生物多样性基因组学与生物奥秘的解析

染色质高级结构与人类疾病

Epigenetic regulation of future expression

动物毒素与生存适应和新药研发

Regulatory T Cell and Immune Therapy

Organization of Midbrain Serotonin System

原位冷冻电子断层成像揭秘病毒激活

Decode and reprogram the yeast genome

植物与病原细菌的战争

Germinal center and long-lived humoral memory

北极游隼的归家之路

mechanism and function: study on the Hedgehog pathway

Aurora, multifaces for tumorigenesis and therapeutic potential

甘忠如：农村娃进北大，跟党走70年

T cell receptor signaling: from mechanisms to therapeutic applications

Developing TCR-based CAR-T cell approach for cancer therapy

Mother-ootheca joint camouflage of stick in a social spider

2021年度学术周

The unconventional STING signaling and epigenetics in regulating IFN responses for the antiviral and anticancer immunity

Cortical control of innate behaviors

Expanding mechanisms and therapeutic targets for neurodegenerative disease

植物的病原物识别通路的交叉互作

RNA调控在精子发生及男性不育中的新功能

CRISPR/Cas technologies for breeding, diagnostics and therapeutics

新时期的稻之道：提供对人类和地球都健康的食品

光驱动合成生物学：从异养细胞工厂到自养细胞工厂

基因编辑技术在基因治疗中的应用研究

DNA damage response and cancer therapy

Cryo-EM Advances RNA Structure Determination

水稻株型形成的分子基础与野生稻驯化

Folding the genome by cohesin

Basal Forebrain Mechanisms of Sleep-Wake Regulation

Stem Cell-Niche Interactions in Regeneration and Stress

陈一友：不寻常的道路

情感和情感障碍的神经环路研究

青藏高原地区两栖爬行动物多样性及进化研究

Linking RNA Processing and Function

新冠病毒S蛋白变异的趋势及其对病毒感染性和抗原性的影响

Mapping whole brain activity and structure at cellular resolution

Functional diversity of GPCR ligand recognition and signaling transduction

Getting your paper published- an editor’s perspective

生物多样性保护与研究进展

Uniting the Genome: Multifaceted Functions of piRNA in the Germline

From Pecking Order to Ketamine — Neural Mechanism of Emotion and Social behavior

Neural mechanisms of itch sensation

Fhb7基因水平转移塑造小麦赤霉病抗性

Discovery of RIPK1 and its implication in human diseases

Activation and Signaling Mechanism of Human Cannabinoid Receptors

Dissecting neural circuit mechanisms of neurodevelopmental disorders

基因组结构变异的检测、表征和功能

纳米生物学：生命科学和物质科学的交汇与碰撞

蝗灾的奥秘：两种信息素的平衡导致蝗虫的群聚

构建亚洲人群遗传演化的古基因组研究

Pyroptosis, inflammation and antitumor immunity

肉苁蓉系统研究与产业化推广

2020年度学术周

Multifunctional & multidimensional super-resolution microscopy

RNA as a Target : Nature does it so well

Life at extremes: on Earth and beyond

如何在《Science》上发表文章

Systematic approaches to studying cancer development and drug response

Molecular Mechanisms of Brain Wiring

A Molecular Arms Race: HIV versus the Immune system

Mechanisms of new gene evolution: the sexual antagonistic selection and de novo origination

Metabolic Reprogramming of Terminally Exhausted CD8+ T-cells by Interleukin-10 Enhances Anti-Tumour Immunity

肿瘤靶向治疗的思考

Molecular Evolution informs Genomic Medicine

Cellular and neural circuit mechanisms of developmental synapse pruning in the cerebellum

Two-Photon In-vivo Imaging & Array Tomography in Large Field CLEM and Intelligent Data Analysis

Ubiquitin Signaling and The DNA Damage Response

Modifications of RNA: their function and role in cancer

tRNA Methylation Is a Global Determinant of Bacterial Multi-Drug Resistance

From breastfeeding to independent feeding: the origins of homeostatic sensing

通过生物进化进行技术创新：为生命世界带来新的化学

Poetry in motion: Increased chromosomal mobility after DNA damage

Epigenetic mechanisms of cellular heterogeneity

Human adaptation to local environments

The NIH Regulome Project

Mechanisms of glucose sensing and biological implications

Making New Neurons to Replenish Lost Neurons in Neurodegenerative Disease

Probing Mechanisms of Transcriptional Regulation by Targeted Factor Perturbations

Self-organization and patterning dynamics in Drosophila

Art of Lecturing: How to Give an Effective Scientific Lecture

Fire and Water are Good Servants but Bad Masters

蛋白质SUMO修饰调控线粒体的应激反应

DYNAMICS OF FUNCTION AND REGULATION OF THE ENDOPLASMIC RETICULUM

Advanced imaging of cellular processes across scales

Design of mouse bispecific antibody for drug development

CryoEM structures of virus assemblies in vitro and in cells

The role of cell of origin and cancer stem cells in glioblastoma

Spermatogenesis role on the evolution of new genes

Mechanism and function of a new genomic imprinting in development & SCNT reprogramming as well as new efforts of the Zhang lab in brain reward system

Reconstruction and rectification of large-scale microscopic brain maps

Brain Science of Hallucination in Schizophrenia and Its Animal Model

Optogenetic Analysis of Biological Neural Networks Across Scales

Single Particle Cryo-EM of Membrane Protein

Basal ganglia and action sequence

Novel single cell mechanobiology approach reveals an intermediate state of integrin αⅡbβ3 that mediates platelet aggregation under disturbed flow

Industrial Level Full Neuron Morphology Screening of Whole Brains

T Cell Exhaustion and PD-1 Immunotherapy

Systematic Analysis of Differential Transcription Factor Binding to Non-Coding Variants in the Human Genome

Gene editing technology in plants: optimization and applications in auxin biology

Nature Metabolism- A New Nature Research Journal

BMC Medicine: scope, threshold and submission

"The essence of knowledge is, having it, to apply it" - Cell & Gene Therapy Today

Bisulfite-free direct detection of 5-methylcytosine and 5-hydroxymethylcytosine at base resolution

Big-data Approaches to Model Cancer Therapy Response and Resistance

ENDOGENOUS CANNABINOIDS AND THE PURSUIT OF REWARD

花粉壁的形成与植物光温敏育性调控

探索免疫之“术” 感悟科研之“道”

蛋白尿和足细胞骨架

Decoding the Regulation and Function of RNA modifications from Epitranscriptomic and Epigenomic Data

Becoming what you smell: adaptive sensing in the olfactory system

高等植物组蛋白甲基化动态调控的分子机理及功能

Resequencing-based rice genetics

Using global proteomics to discover new anti-TB pathways of macrophages

Two is better than one: the mechanism of the dimerization of WRKY transcription factors

The Molecular Motors, KIFs and Intracellular Transport: Regulation of Neuronal Function, Development and Diseases

Prostate lineage hierarchy and homeostasis

Mitochondria in Health and Disease

Toward a unified computational approach to biophysical chemistry, single-cell dynamics, and evolutionary biology

Using fruit flies to understand sleep regulation and function

PTM of glycosylation in cell adhesion and EMT of cancer cells and diseases

Inflammasome assembly and gasdermin D biology in health and disease

Machine Learning to Quantify Brain Activity from Astrocyte Imaging Data

Convergence of TDP43 and BDNF signaling hubs in regulation of synaptic plasticity and behavior

Epigenomic regulation of enhancers: from adipogenesis, development to cancer

Population genomics of lepidopterans

卵源因子决定脊椎动物体轴的机制

The MYC2/MED25 Complex Controls the Activation and Termination of Jasmonate Signaling

不忘初心，方得始终——为了生命科学的人生

Modeling human brain development and developmental diseases using hiPSCs

Deconstructing endodermal organ development to reconstruct organs from stem cells

杂交稻育性控制的分子遗传基础

肠道微生物介导蚊虫与病原物互作机制及应用

Organizations of Neuronal Synapses: A New Phase of Research

Understanding of oogenesis with a novel reconstitution system

Gene editing strategies to cure human diseases postnatally

Precision medicine and long-term management of Parkinson’s Disease

Structural Biology: Getting in on the Ground Floor

Epigenetic regulation in development, aging and disease

Phase separation and control of cell identity in mammalian cells

Defining how problematic DNA replication impacts on chromosome segregation

Function map of viral genome at single nucleotide resolution